FULLERTON SPACE-GRADE PROBIOTICS

Space Yeast Raw Material Introduction

1

Space Flight (Real Space Mission)

Original Strain Selection: Carefully chosen from a resource bank of high-performance, high-potential application strains. Spacecraft: Carried aboard the Shenzhou-11 spacecraft and the Tiangong-2 space laboratory. Orbital Parameters: Flight altitude: 393 km; In-orbit flight duration: 31 days for lactic acid bacteria, 63 days for yeast. Space Environment: Subjected to extreme conditions unreplicable on Earth—such as microgravity, intense cosmic radiation, high vacuum, extreme temperature variations, and weak magnetic fields—forcibly inducing endogenous gene mutations in the strains.

2

Ground Super-Screening (Core Technology)

After returning to Earth, the R&D team employed the following methods to screen from hundreds of billions of mutant strains: High-throughput screening and in vitro functional screening models. Targeted screening for acid tolerance, bile salt tolerance, intestinal colonization capacity, antioxidant, anti-inflammatory, and metabolic regulation properties. Result: Four "space-grade superpower" strains with Chinese invention patents were ultimately selected:

SS18-119 (Space Lactiplantibacillus plantarum)

SS18-5 (Space Lactiplantibacillus plantarum)

9-35 (Space Limosilactobacillus reuteriFullarton-9-35)

ST26-13 (Space-Mutated Saccharomyces cerevisiae)

3

Summary of Technological Strength

One of the very few enterprises in China possessing independent intellectual property rights in both the "Space Probiotics" and "Space Brewer's Yeast" sectors. Holds 22 Chinese National Invention Patents + 1 PCT International Patent. Maintains a library of over 7,000 space-mutated microbial strains. Research outcomes have been incorporated into standard Chinese university textbooks. Recognized as a benchmark enterprise for the commercialization of aerospace technology.

R&D Background

The Fullarton Space-Grade Probiotics and Space Yeast raw material series are the outcomes of a national-level space microbial breeding project under China's manned space program. This achievement stems from the collaboration between Fullarton Bioengineering Technology (Beijing) Co., Ltd., a Chinese high-tech enterprise, and leading research institutions including the College of Food Science and Engineering of Jilin University, the Institute of Microbiology of the Chinese Academy of Sciences, the China National Research Institute of Food and Fermentation Industries, and the University of Adelaide.

Space-grade antioxidant vanguard

The space-grade antioxidant vanguard, offering liver protection, anti-aging benefits, high viability, and strong colonization.

Patent No.: ZL201810113533.9

Space Lactiplantibacillus plantarum SS18-119

Powerful Antioxidant + Liver Protection + Anti-Lipid Peroxidation

  • Extremely strong antioxidant capacity:

    DPPH free radical scavenging rate 85.6%; increases SOD activity by 6.9%.

  • Anti-lipid peroxidation: 

    53.8% improvement compared to the original ground strain, protecting cell membranes and delaying aging.

  • Liver protection & alcohol metabolism:

     Significantly alleviates alcoholic fatty liver disease and reduces liver inflammation factors (TNF-α, IL-6).

  • High stress tolerance: 

    Gastric acid (3h) survival rate 93.7%; bile salt (8h) survival rate 71.6%.

  • Strong exopolysaccharide (EPS) production: 

    Output of self-"protective + immune-activating" substances increased by 53.85%.

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Space-grade antioxidant vanguard

The space-grade blood sugar guardian, stabilizing glucose, regulating metabolism, and aiding weight control

Patent No.: ZL201711372227.9

Space Lactiplantibacillus plantarum SS18-5

Top-tier Blood Sugar Management + Metabolic Regulation + Weight Management

  • Potent blood sugar management:

     α-Glucosidase inhibition rate 90.47% (69.86% higher than the ground strain, 5.97% higher than LGG)

  • Stabilizes postprandial blood glucose: 

    Independent of insulin, with no risk of hypoglycemia; suitable for individuals with elevated blood sugar levels.

  • Regulates metabolism & reduces fat accumulation: 

    Improves insulin sensitivity and inhibits fat synthesis.

  • Strengthens intestinal barrier:

     Inhibits harmful bacteria, reduces endotoxins, and improves metabolic disorders.

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Space-grade antioxidant vanguard

The space-grade gut stability expert, featuring strong colonization, H. pylori inhibition, anti-inflammatory action, and microbiota balance.

Patent No.: ZL201711346871.9

Space Limosilactobacillus reuteri 9-35 (Fullarton-9-35)

Gut Stability Champion + Strong Colonization + H. pylori Inhibition & Anti-inflammatory

  • Superior intestinal colonization:

     Hydrophobicity (adhesion force) doubled compared to the ground strain (78.97%).

  • Potently inhibits Helicobacter pylori:

     Inhibition rate 91.37%; inhibition rates against E. coli and S. aureus close to 100%.

  • High reuterin production:

     A natural broad-spectrum antimicrobial substance that balances gut microbiota.

  • Anti-inflammatory & repair: 

    Significantly reduces TNF-α, IL-1β, IL-6, alleviating symptoms of IBS, constipation, and diarrhea.

  • Exceptional gastrointestinal tolerance: 

    After simulated gastrointestinal fluid challenge, viable cell count decline is <2 log units.

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Space-Mutated Brewer's Yeast ST26-13

The benchmark for space craft brewing yeast, reducing costs, improving quality, enhancing health value, and delivering outstanding flavor.

Patent No.: ZL202010385930.9

Space-Mutated Brewer's Yeast ST26-13

Specialized for Space Craft Brewing + Low Diacetyl + High Glutathione + Unique Flavor Profile

  • China's first patented space brewer's yeast.

  • Strong low-temperature fermentation capability: 

    Suitable for craft brewing processes, shortens fermentation cycles.

  • Exceptionally low diacetyl: 

    Results in a crisp beer body without off-flavors.

  • High glutathione content: 

    Provides antioxidant and liver-protective benefits, enhancing the health value of beer.

  • Unique aroma & full-bodied taste:

     Space mutation yields richer fruity/floral notes and a distinctive clove-like floral aroma.

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